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PSYCHCAST™ CME
 

sinaiAdvances in the Diagnosis, Pathogenesis, and Management of Fibromyalgia Syndrome PsychCast™

Psychophysical and Neurochemical Abnormalities of Pain Processing in Fibromyalgia (31:04 Minutes)

Author: Roland Staud, MD, and Michael Spaeth, MD

This is a 30 minute PsychCast™ podcast with an Internet component.

This CME Expert Review PsychCast™ is jointly sponsored by the Mount Sinai School of Medicine and MBL Communications.

Release Date: May 2008
Termination Date: May 31, 2010

Funding for this activity has been provided through an educational grant from Eli Lilly and Company and Pfizer Inc.

Faculty Affiliations and Disclosures:

Dr. Staud is professor of medicine in the Division of Rheumatology and Clinical Immunology, McKnight Brain Institute, at the University of Florida in Gainesville. Dr. Staud is a consultant to Eli Lilly, Jazz, and Pfizer; is on the speaker’s bureau of Merck; and is supported by National Institutes of Health grants NS-38767 and AR053541.

Dr. Spaeth is medical director of the Center for Clinical Rheumatology Research in Graefelfing/Munich, Germany. Dr. Spaeth is a consultant to Allergan, Eli Lilly, Jazz, and Pierre Fabre Medicament; and is on the speaker’s bureaus of Eli Lilly and Pierre Fabre Medicament.

Learning Objectives

  • Recognize the pain processing abnormalities in fibromyalgia and their peripheral and central components.
  • Review new approaches for the prevention and treatment of fibromyalgia and other chronic pain syndromes.

Target Audience: This activity is designed to meet the educational needs of psychiatrists.

Peer Reviewers:

Eric Hollander, MD, does not have an affiliation with or financial interest in any organization that might pose a conflict of interest. This activity has been peer-reviewed and approved by Eric Hollander, MD, Professor of Psychiatry and Chair at Mount Sinai School of Medicine. Review Date: February 15, 2008

Accreditation Statement: This activity has been planned and implemented in accordance with the Essentials and Standards of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the Mount Sinai School of Medicine and MBL Communications, Inc. The Mount Sinai School of Medicine is accredited by the ACCME to provide continuing medical education for physicians.

Credit Designation: The Mount Sinai School of Medicine designates this educational activity for a maximum of 0.5 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Faculty Disclosure Policy Statement: It is the policy of Mount Sinai School of Medicine to ensure objectivity, balance, independence, transparency, and scientific rigor in all CME-sponsored educational activities. All faculty participating in the planning or implementation of a sponsored activity are expected to disclose to the audience any relevant financial relationships and to assist in resolving any conflict of interest that may arise from the relationship. Presenters must also make a meaningful disclosure to the audience of their discussions of unlabeled or unapproved drugs or devices. This information will be available as part of the course material.

Disclaimer: These are the opinions of the authors not of the sponsors or supporters. For more information, contact MBL Communications at cme@mblcommunications.com.

Minimum Hardware/Software Requirements

Macintosh: PowerPC processor, Mac OS 8.6, 9.0.4, 9.1, or Mac OS X, 64MB of RAM, 24MB of available hard-disk space, and Safari 1.x or 2.x.
Windows PC: Intel Pentium processor, Microsoft Windows 95 OSR 2.0, Windows 98 and 98 SE, Windows Millennium Edition, Windows NT 4.0 with Service Pack 5, Windows 2000, or Windows XP, 64MB of RAM, 24MB of available hard-disk space, and Internet Explorer 6.x and newer or Firefox 1.x and newer.

This CME Activity and Posttest information file is a PDF (Portable Document Format) document. To view this file, you will need Adobe Acrobat Reader, which is available free at www.adobe.com. Follow the instructions on that page to download and install the software.

Advances in the Diagnosis, Pathogenesis, and Management of Fibromyalgia Syndrome PsychCast™
Psychophysical and Neurochemical Abnormalities of Pain Processing in Fibromyalgia
(31:04 Minutes)
Author: Roland Staud, MD, and Michael Spaeth, MD

Abstract
Fibromyalgia pain is frequent in the general population, but its pathogenesis is only partially understood. Patients with fibromyalgia lack consistent tissue abnormalities but display features of hyperalgesia (increased sensitivity to painful stimuli) and allodynia (lowered pain threshold). Many recent fibromyalgia studies have demonstrated central nervous system (CNS) pain processing abnormalities, including abnormal temporal summation of pain. In the CNS, persistent nociceptive input from peripheral tissues can lead to neuroplastic changes resulting in central sensitization and pain. This mechanism appears to represent a hallmark of fibromyalgia and many other chronic pain syndromes, including irritable bowel syndrome, temporomandibular disorder, migraine, and low back pain. Importantly, after central sensitization has been established, only minimal peripheral input is required for the maintenance of the chronic pain state. Additional factors, including pain-related negative affect and poor sleep have been shown to significantly contribute to clinical fibromyalgia pain. Better understanding of these mechanisms and their relationship to central sensitization and clinical pain will provide new approaches for the prevention and treatment of fibromyalgia and other chronic pain syndromes.

To receive credit for this activity: Listen to the PsychCast™, reflect on the material presented, and complete the online CME Posttest/Evaluation here or to submit the CME Posttest/Evaluation by mail or fax, download a PDF here. To obtain credit, you should score 70% or better. The estimated time to complete the PsychCast™ and the posttest and evaluation is .5 hour. Successful completion of the posttest and evaluation will allow you to claim credit and print a certificate.

Early submission of this posttest is encouraged: please submit by May 1, 2010 to be eligible for credit. If you have any questions, please e-mail cme@mblcommunications.com.

Read the extended CME supplement related to this PsychCast™ activity here


Supported by Eli Lilly and Company and Pfizer Inc.
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